Qualitative Assessment of Factors Affecting Prevention of Mother-To-Child Transmission (PMTCT) of HIV Programs in University Teaching Hospitals in Anambra State, Nigeria
Abstract:
Background: Human Immunodeficiency Virus (HIV) infection in newborns is one of the leading causes of
infant mortality globally and accounted for about 1.8million childhood deaths
in 2010. Despite international interventions aimed at reducing pediatric
infections at antenatal clinic entry points, however, there is still limited
access and utilization of Prevention of Mother to Child Transmission (PMTCT) services
resulting in low target coverage due to obstacles existing at facility,
community and state levels. Anambra State still records a low patronage of
PMTCT interventions by pregnant mothers.
Objective: This study was carried out to determine the
factors affecting prevention of mother-to-child transmission (PMTCT) of HIV
programs in university teaching hospitals in Anambra state, Nigeria
qualitatively.
Methods: This is a
descriptive cross-sectional study involving 128 randomly selected HIV positive pregnant
women attending antenatal care clinics and service providers of two purposively
selected teaching hospitals in Anambra state, Nigeria. Qualitative data were
obtained through focus group discussions and key in-depth informant interviews.
Data analysis was carried out using NVivo version 9 qualitative data analysis
Software.
Results: The findings
of this work show that ninety-nine percent (99%) of the study participants knew
that HIV was a deadly virus transmitted through sex and other blood contact routes.
Seventy six percent (76%) of the participants knew that HIV could be
transmitted from mother to child, while about 53% of them knew the major ways
of MTCT of HIV. The participants that did not know how HIV could be passed from
mother to child were 41%. Others factors are lack of awareness and knowledge
about HCT, late presentation at ANC clinics, low numbers of PMTCT centers
within locality of respondents, poor involvement of male partners/spouses and
stigma were the main reasons cited for poor utilization of PMTCT programs in
the state.
Conclusion: The study
highlights a referral linkage of traditional birth attendants to health
facilities for PMTCT interventions in the state to have profound impact on the
health of the mother, child and nation at large.
Keywords: Human
immunodeficiency virus (HIV), Prevention of mother to child transmission
(PMTCT), HIV counselling and testing, Antenatal Care.
References:
[1].
Anigilaje, E.A., Ageda, B.R. and Nweke,
N.O. (2016). Barriers to uptake of prevention of mother-to-child transmission
of HIV services among mothers of vertically infected HIV-seropositive infants
in Makurdi, Nigeria. Dove Medical Press, 10:57-72.
[2].
Barker, P.M., Mphatswe, W. and Rollins,
N. (2011). “Antiretroviral drugs in the cupboard are not enough: the impact of
health systems' performance on mother-to-child transmission of HIV,” Journal of
Acquired Immune Deficiency Syndromes, Vol. 56, No. 2, pp. e45–e48.
[3].
Chinkonde, J.R., Sundby, J. and
Martinson, F. (2009). “The prevention of mother-to-child HIV transmission
programme in Lilongwe, Malawi: why do so many women drop out,” Reproductive
Health Matters, Vol. 17, No. 33, pp. 143–151.
[4].
Dabis, F., Newell, M.L., L. Fransen, L. et al. (2000). “Prevention of
mother-to-child transmission of HIV in developing countries: recommendations
for practice,” Health Policy and Planning, vol. 15, no. 1, pp. 34–42.
[5]. Deressa, W., Seme, A., Asefa, A.,
Teshome, G. and Enqusellassie, F. (2014). Utilization of PMTCT services and associated factors among pregnant women
attending antenatal clinics in Addis Ababa, Ethiopia. BMC Pregnancy and
Childbirth Vol. 14 p.328-341.
[6]. Ezeanolue, E.E., Obiefune, M.C., Yang, W., Obaro,
S.K., Ezeanolue, C.O., Ogedegbe, G.G. (2013). Comparative effectiveness of
congregation-versus clinic-based approach to prevention of mother-to-child HIV
transmission: study protocol for a cluster randomized controlled trial. Implement Sci.
8(1):62.
[7].
Federal HIV/AIDS Prevention and Control
Office (2011). In Multi-sectoral HIV/AIDS Response Annual Monitoring and
Evaluation Report 202 EFY.
[8]. Federal Ministry of Health. (2003).
National HIV/AIDS and Reproductive Health Survey (NARHS).
[9].
Link B. and Phelan, J. (2001). On stigma
and its public health implications. Paper presented at: Stigma and Global
Health: Developing a Research Agenda; Bethesda, MD. Washington: National
Institutes of Health.
[10].
Manzi, M., Zachariah, R., Teck, R. etal. (2005). “High acceptability of
voluntary counselling and HIV-testing but unacceptable loss to follow up in a
prevention of mother-to-child HIV transmission programme in rural Malawi:
scaling-up requires a different way of acting,” Tropical Medicine and
International Health, Vol. 10, No. 12, pp. 1242–1250.
[11].
NACA (2012). National
Agency for the Control of AIDS; Nigeria Global AIDS Response, Country Progress
Report. Nigeria: Abuja.
[12]. National Agency for the Control of
AIDS (2011). Factsheet 2011: Update on the HIV/AIDS Epidemic and Response in
Nigeria.
[13].
Nguyen, T.A., Oosterhoff, P., Ngoc,
Y.P., Wright, P. and Hardon, A. (2008). Barriers to access prevention of
mother-to-child transmission for HIV-positive women in a well-resourced setting
in Vietnam. AIDS Res Ther 17:5-7.
[14].
Nkwo, P. (2013).
Prevention of mother to child transmission of Human Immunodeficiency Virus: The
Nigerian perspective. Annals of
Medical and Health sciences Research. 2(1):56–65.
[15].
Painter, T.M., Diaby, K.L., Matia, D.M.,
etal. (2004). “Women's reasons for
not participating in follow up visits before starting short course
antiretroviral prophylaxis for prevention of mother to child transmission of
HIV: qualitative interview study,” British Medical Journal, Vol. 329, No. 7465,
pp. 543–546.
[16].
Siegfried, N., van der Merwe, L.,
Brocklehurst, P. and Sint, T.T. (2011). “Antiretrovirals for reducing the risk
of mother-to-child transmission of HIV infection,” Cochrane Database of
Systematic Reviews, no. 7, p. CD003510.
[17].
Theilgaard, Z.P., Katzenstein, T.L.,
Chiduo, M.G. et al. (2011).
“Addressing the fear and consequences of stigmatization—a necessary step
towards making HAART accessible to women in Tanzania: a qualitative study,”
AIDS Research and Therapy, Vol. 8, No. 1, p. 28.
[18]. UNAIDS, (2013).
Progress report on the Global Plan towards the elimination of new HIV
infections among children by 2015 and keeping their mothers alive.
[19].
UNAIDS (2011). UBRAF
2012-2015 Country Case Study: Nigeria. Geneva.
[20]. United
Nations AIDS Program (2010). http://www.unaids.org/globalreport/Global_report.htm
[21].
United Nations AIDS Program (2008).
Epidemiological Fact Sheet on HIV and AIDS: Core Data on Epidemiology and
Response. Ethiopia.
[22].
UNAIDS (2005). HIV-related stigma,
discrimination and human rights violations: case studies of successful
programs.
[23].
World Health Organization (2005). The
World Health Report, Geneva, Switzerland.
[24].
World Health Organization (2006).
Antiretroviral Drugs for treating Pregnant women and preventing infection in
Infants: Towards Universal Access: Recommendations for a Public Health
Approach, WHO, Geneva, Switzerland.
[25].
World Health Organization (2007).
Prevention of Mother to Child Transmission (PMTCT). Briefing note, Department
of HIV/AIDS.
[26].
World Health Organization (2010). New
guidance on prevention of mother-to-child transmission of HIV and infant
feeding in the context of HIV.
[27].
World Health Organization (2010).
“Towards Universal Access Progress Report.
[28].
Zachariah, R., Ford, N., Philips, M., etal. (2009). Task shifting in HIV/AIDS:
Opportunities, challenges and proposed actions for sub-Saharan Africa. Trans
R Soc Trop Med Hyg.103:549–558.