Efficacious Outcome of Peripheral Retinal Laser Photocoagulation to Severe Non-Proliferative Diabetic Retinopathy in Young-onset Type 1 Diabetic Mellitus: A Case Report

Abstract:
The rising prevalence of childhood type 1 diabetes and
type 2 diabetes increases the number of children and adolescents at risk of
visual loss due to the presence of diabetic retinopathy (DR). We report herein a case of a young adult who presented
to the emergency department with sudden vision loss in both eyes. She had been
diagnosed with type 1 diabetes mellitus (T1DM) five years ago. Patient with severe NPDR was
monitored using OCT (optical coherence
tomography) which revealed peri-papillary cotton wool spots, intraretinal haemorrhages,
and retinal microaneurysms (MA). The
patient was urgently hospitalized and prescribed to be under insulin therapy.
DR was developed and progressed to severe NPDR. The investigation continued
through multiple OCTs. Finally, she was prescribed to be under laser therapy
with multiple sessions of PRP (Peripheral Retinal laser Photocoagulation).
Subsequently, the macular edema resolved and the patient was satisfied with her
vision after six sessions of PRP. Literature collected from various countries stated
that diabetic retinopathy can be successfully treated with laser therapy. We
discuss the importance of recognizing and treating the patient with laser
therapy. There is a need for further research on laser therapy in NPDR among young-onset
diabetic mellitus.
References:
[1].
Everett, L. A., Paulus, Y. M., 2021, Laser Therapy in the Treatment of
Diabetic Retinopathy and Diabetic Macular Edema, Curr Diab Rep, 21(9):35,
https://doi.org/10.1007/s11892-021-01403-6.
[2].
CDC, 2020, Government. Diabetic Retinopathy, https://www.cdc.gov/visionhealth/pdf/factsheet.pdf.
[3]. Suganya,
M., 2024, Letter to Editor: Relieving menopausal symptoms through yoga
practice. International Journal of Nutrition, Pharmacology, Neurological
Diseases, 14(4):488, https://journals.lww.com/ijnp/fulltext/2024/14040/letter_to_editor__relieving_menopausal_symptoms.15.aspx.
[4].
Suganya, M.,
Maragatham, S., Sheela, P., 2024, Assessment on Health Status of Adult Patients
with Osteoarthritis of the Lower Limb by Western Ontario and McMaster’s
Universities Osteoarthritis Index (WOMAC): A Study in Chennai City, Texila
International Journal of Public Health, Special Issue:1-8, https://doi.org/10.21522/TIJPH.2013.SE.24.02.art007.
[5].
Bhuvaneswari, R., Diviya, M., Subramanian, M., Maranan, R., Josphineleela,
R., 2023, Hybrid generative model for grading the severity of diabetic
retinopathy images. Computer Methods in Biomechanics and Biomedical
Engineering: Imaging & Visualization, 11(7), https://doi.org/10.1080/21681163.2023.2266048.
[6].
Jyotheeswar, S., Kanimozhi, K. V., 2022, Prediction
of Diabetic Retinopathy using Novel Decision Tree Method in Comparison with
Support Vector Machine Model to Improve Accuracy, Proceedings of the
International Conference on Sustainable Computing and Data Communication
Systems (ICSCDS), https://ieeexplore.ieee.org/stamp/stamp.jsp?arnumber=9760842.
[7].
Angela, J.,
Michael Javaheri, Hamid Hosseini, Pradeep, S., Prasad, 2023, Purtscher‑like
retinopathy in a 19‑year‑old with maturity‑onset diabetes of the young: a case
report, Journal of Medical Case Reports, 17:255;1-4, https://doi.org/10.1186/s13256-023-03985-z.
[8]. Farheen
Naz, JenilaRani, D., 2022, Detection and Comparison of Diabetic Retinopathy
using Thresholding Algorithm and CMeans Clustering Algorithm, Journal of
Pharmaceutical Negative Results, 14(4), https://www.pnrjournal.com/index.php/home/article/view/899.
[9]. Suganya, M., Padmapriya, D., 2024, Determinants and
levels of depression among young adult patients with epilepsy: a
cross-sectional study in a Tertiary Care Hospital, Tamilnadu, India, International
Journal of Nutrition, Pharmacology, Neurological Diseases, 14(4): 432-436, https://doi.org/10.4103/ijnpnd.ijnpnd_112_24.
[10]. Suganya, M., Kalabarathi, S., 2024, Efficacious
Maintenance-Electroconvulsive Therapy (m-ECT) and Antipsychotic Medication for
Schizophrenia Spectrum Disorder in a Young Adult Woman in Chennai, India: A
Case Report. International Journal of Nutrition, Pharmacology, Neurological
Diseases, 14(3):390-392, https://doi.org/10.4103/ijnpnd.ijnpnd_42_24.
[11]. Ebrahimi, M. H., Gharibi, H., 2016, A case study of a
patient with diabetic retinopathy, Diab Met Syndr: Clin Res Rev, http://dx.doi.org/10.1016/j.dsx.2016.01.022.
[12]. Suganya, M., KalaBarathi, S., 2024, Association of
body mass index with dietary intake and self-care health activities of mothers
after postpartum: A mixed-method research in Chennai City, India, Int J Nutr
Pharmacol Neurol Dis, 14:52-7, https://doi.org/10.4103/ijnpnd.ijnpnd_71_23.
[13]. Sridhar,
S., Pradeep Kandhasamy, J., Sinthuja, M., Sterlin Minish, T. N., 2021,
WITHDRAWN: Diabetic retinopathy detection using convolutional nueral networks
algorithm, Materials Today: Proceedings, ISSN 2214-7853, https://doi.org/10.1016/j.matpr.2021.01.059.
[14]. Ramakrishnan, A.,
Veeramani, P. A., et al., 2024, Association of Various Optical Coherence
Tomographic Patterns of Diabetic Macular Edema with Central Subfield Thickness
and Visual Acuity: A Cross-Sectional Observational Study, Cureus.
19,16(9),
https://assets.cureus.com/uploads/original_article/pdf/294904/20241019-1529365-17tn37.pdf.