Abstract:

Diabetes predominantly affects the microvascular circulation of the retina. Diabetic retinopathy is a severe complication of diabetes mellitus and a leading cause of diminution of vision. Preventing irreversible vision loss requires early diagnosis of retinal vascular abnormalities. Fundus fluorescein angiography (FFA) is the gold standard for assessing retinal vascular abnormalities and optical coherence tomography confirms the diagnosis. The purpose of this case report was to examine the effectiveness of ranibizumab intravitreal therapy in diabetic patients as well as the usefulness of FFA in evaluating peripheral retinal vascular abnormalities. A 67-year-old adult presented to the emergency department in a tertiary care hospital in Chennai, India, with the sudden onset of painless vision loss in the left eye. Due to irregular medication, he developed diabetic macular oedema. Optical coherence tomography confirmed the presence of macular edema in the left eye and consent was obtained for unilateral pan-retinal photocoagulation (PRP). Despite grid laser, the macular edema persisted and after PRP it was reduced. FFA assisted in treating macular oedema by detecting peripheral retinal ischaemia and administering anti-vascular endothelial growth factor injection (Ranibizumab). The patient's best-corrected visual acuity was improved from 6/36 to 6/9 in the left eye. Research are needed to improve glycaemic management and prompt therapies to help patients with diabetic retinopathy see better and live better lives.

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