Abstract:

Guided Bone Regeneration (GBR) is a crucial technique in promoting bone growth in areas where bone tissue is deficient. The use of GBR membranes is essential in preventing the resorption of new bone tissue by the body. This study aims to develop an electrospun GBR membrane utilizing Hyaluronic Acid (HA) with Tricalcium Phosphate (TCP) and quercetin-doped silver to explore its potential in promoting bone regeneration. The novel HA/TCP/quercetin-doped silver membrane demonstrated favorable biocompatibility, mechanical properties, and potential to enhance bone growth. This makes it a promising candidate for clinical applications in GBR. The membrane exhibited superior mechanical properties, biocompatibility, and ability to promote bone growth both in vitro and in vivo, indicating its potential as an innovative material for GBR.

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