Abstract:

Albizia saman is a tree of the Fabaceae family that has been used for ethnomedical purposes since olden times. Prior investigations have reported probable medicinal value against a wide array of ailments, which may be attributed to its varied phytochemical composition. Thence, there is a requirement for comprehensive studies on its efficacy against individual pathogens and their mechanisms. The present study is an effort to encompass a comprehensive description of the antimicrobial, anti-inflammatory, and antioxidant potential of A. saman extract with major emphasis against Candida albicans. Various microbial methods have been used for the determination of the antimicrobial potential of A. saman extract, including disc diffusion, well diffusion, streak plate, and various dilution techniques. The anti-inflammatory and antioxidant activities were assayed in vitro and in vivo by various models. A. saman extract exhibited significant antimicrobial activity against the tested pathogens, C. albicans. It also potent anti-inflammatory and anti-oxidant activity. Phytochemical screening for A. The phytochemical screening of the leaf extract of Saman revealed several important phytochemicals: tannins, alkaloids, carbohydrates, saponins, flavonoids, protein, phenol, and ninhydrin. In view of the antimicrobial, anti-inflammatory and antioxidant properties of the extracts of A. saman, it holds immense potential in the development of new therapeutic agents. Findings of the present study clearly show that Albizia saman could be utilized to reveal the traditional uses of this plant, and to discover new therapeutic uses.

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