Fabrication and Characterization of PVA Tricalcium Phosphate and Quercetin-doped Strontium Membranes for Guided Bone Regeneration
Abstract:
Guided Bone Regeneration (GBR) is a technique used in
reconstructive dentistry to address small defects around dental implants and to
facilitate bone regeneration in alveolar defects. It involves the use of bone
grafts and barrier membranes to promote the selective growth of bone tissue
while preventing soft tissue infiltration. Surface structural morphology
analysis using scanning electron microscopy (SEM) revealed notable differences
between the fabricated membrane samples. A comparative assessment indicated an
increase in both porosity and nanofiber size upon the addition of strontium
nanoparticles. This alteration was further corroborated by the observed
decrease in hydrophilicity, as evidenced by an increase in the contact angle
from the typical 30 degrees to 58.7 degrees. Our
study offers a promising avenue for advancing guided bone regeneration through
the development of PVA-TCP membranes tailored with quercetin and strontium.
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