Green Synthesis of Silver Nanoparticles Using Coriandrum sativum Extract and Their Antioxidant, Anti-inflammatory and Antibacterial Activities Against UTI Pathogens
Abstract:
This study explored the green synthesis of silver nanoparticles
(AgNPs) utilizing Coriandrum sativum extract and investigated their potential
applications in terms of antibacterial and antioxidant activities. UV‒visible
absorption spectra revealed a distinctive absorption peak at 450 nm, indicating
successful AgNPs synthesis and stabilization with Coriandrum sativum extract
and the TEM analysis revealed the shape to be spherical and size was found to
range between 5-25 nm. Antibacterial assays revealed concentration-dependent
zones of inhibition against Staphylococcus aureus, Escherichia coli,
Pseudomonas sp., and Klebsiella sp., confirming the efficacy of Coriandrum
sativum-mediated AgNPs as antibacterial agents. The AgNPs exhibited significant
antioxidant properties, with concentration-dependent scavenging activities
observed in the DPPH, hydrogen peroxide, and FRAP assays. Protein denaturation
assays revealed concentration-dependent effects, suggesting potential
applications in biological and medicinal contexts. Additionally, membrane
stabilization assays revealed the robust concentration-dependent impact of
Coriandrum sativum-mediated AgNPs, underscoring their promising role in diverse
applications, from antibacterial treatments to antioxidant therapies and
protein stability studies.
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