Association of Microalbuminuria in Patient with Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study in A Tertiary Care Centre

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DOI: 10.21522/TIJPH.2013.SE.24.05.Art033

Authors : Maghimaa M, Deepthi V, Kannan R, Kanimozhi D, Nanda Gopal S

Abstract:

NAFLD (Nonalcoholic Fatty Liver Disease) is a prevalent chronic liver disorder characterized by metabolic abnormalities. Microalbuminuria have been linked to cardiovascular and renal diseases, but its association with NAFLD remains underexplored. This cross-sectional study assessed urine microalbumin levels in patients diagnosed with NAFLD. Demographic data, NAFLD grading, and microalbuminuria status were analyzed in non-NAFLD and NAFLD groups. Statistical analysis has been performed to evaluate the associations. Males were more common than females among NAFLD patients (n=100), particularly in the age range of 41 to 60. Compared to non-NAFLD controls (0%), NAFLD patients (76%) had a considerably higher prevalence of microalbuminuria. BMI showed no significant association with NAFLD prevalence. NAFLD grading revealed Grade 1 as the most prevalent (52%), followed by Grade 2 (32%) and Grade 3 (16%). Our findings demonstrate a strong association between microalbuminuria and NAFLD, suggesting a potential link with adverse cardiovascular and renal outcomes. Monitoring microalbuminuria in NAFLD patients may aid in risk stratification and management. There is a need to conduct larger population-based-randomized studies.

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