A Review of Spondias pinnata (L.f.) Kurz's Phytochemical Constituents, Traditional Uses, and Pharmacological Activities: An Important Medicinal Plant in Ayurveda
Abstract:
Spondias pinnata (L.f.)
Kurz, commonly known as wild mango or hog plum, is a medicinal tree belonging
to the family Anacardiaceae, extensively utilized in traditional systems and
codified systems of medicines across the Indian subcontinent and Southeast
Asia. Plant parts including roots, bark, leaves, fruits, and seeds are used for
medicinal purposes to treat a variety of ailments. Phytochemical analysis has
revealed that the presence of various bioactive compounds such as flavonoids,
tannins, phenolic acids, saponins, and essential oils, which contribute to its
pharmacological activities. Essential oil is rich in monoterpene and
sesquiterpene compounds such as α-pinene, caryophyllene, and geraniol.
Additionally, other phytoconstituents including β-sitosterol, gallic acid,
caffeic acid, and alantolactone have been identified from different parts of
the plant. Recent research highlights its antioxidant, anti-inflammatory,
antimicrobial, and antidiabetic properties, further validating its traditional
uses and suggesting potential for the development of novel therapeutic agents.
This review provides a comprehensive overview of the phytochemical properties
of S. pinnata, offering insights that may be valuable for future research and
the establishment of effective natural drugs.
References:
[1].
Soumyanath, A. 2018, Review of
Plants with Anti-Diabetes Mellitus Properties Plants with Anti-Diabetes
Mellitus Properties. By Appian Subramoniam. CRC Press . 2016 . 591 pp, $119.
ISBN 9781482249897. Journal of natural products.
[2].
S. Swathi, S.S., & K.
Lakshman, K.L. 2022, Phytopharmacological and Biological Exertion of Spondias pinnata: (A Review). Oriental Journal Of Chemistry.
[3].
Ndukwe IG, Bello AI, Habila
JD, John C. 2007, Phytochemical and antimicrobial screening of the crude
petroleum spirit and methanol extracts of the stem bark, leaves and roots of
Ficus thoningii (blume). Afr J
Biotechnol. 6:2645–2649.
[4].
Oryema C, Ziraba RB, Odyek O,
Omagor N, Opio A. 2011, Phytochemical properties and toxicity to brine shrimp
of medicinal plants in Erute county, Lira district, Uganda. J Med Plant Res. 5:5450–5457.
[5].
Airy Shaw, H.K.. & Forman,
L.L. 1967, The genus Spondias L. (Anacardiaceae) in tropical Asia. Kew Bull. 21: 1 – 19.
[6].
Chandra, D. & Mukherjee,
S.K. 2000, Anacardiaceae. In:Singh, N.P., Vohra, J.N., Hajra, P.K. & Singh,
D.K. (eds.) Fl. India. Botanical Survey of India, Culcutta. pp. 435 – 510.
[7].
Mabberley's Plant-book A
Portable Dictionary of Plants, their Classification and Uses , pp. 474 - 482
DOI: https://doi.org/10.1017/9781316335581 Cambridge University Press 2017
[8].
POWO, 2024, Plants of the
World Online. Facilitated by the Royal Botanic Gardens, Kew. Published on the
Internet; https://powo.science.kew.org/Retrieved 29 August 2024.
[9].
Bora, N.S, Kakoti B, Gogoi B,
Goswami AK. 2014, Ethno-medicinal claims, phytochemistry and pharmacology of Spondias pinnata: A review.
International Journal of Pharmaceutical
Sciences and Research 5: 1138-1145.
[10].
Salma Sameh, Eman Al-Sayed,
Rola M. Labib, Abdel Nasser B. Singab, 2019, Comparative metabolic profiling of
essential oils from Spondias pinnata
(Linn. F.) Kurz and characterization of their antibacterial activities,
Industrial Crops and Products, Volume 137, 468-474.
[11].
Hazra B, Biswas S, Mandal N. 2008,
Antioxidant and free radical scavenging activity of Spondias pinnata. BMC
Complement Altern Med. 8:63.
[12].
Li R, Yang J-J, Song X-Z, Wang
Y-F, Corlett RT, Xu Y-K, Hu H-B. 2020, Chemical Composition and the Cytotoxic,
Antimicrobial, and Anti-Inflammatory Activities of the Fruit Peel Essential Oil
from Spondias pinnata (Anacardiaceae)
in Xishuangbanna, Southwest China. Molecules.
25(2):343.
[13].
Santos ÉMD, Ataide JA, Coco
JC, Fava ALM, Silvério LAL, Sueiro AC, Silva JRA, Lopes AM, Paiva-Santos AC,
Mazzola PG. 2023, Spondias sp:
Shedding Light on Its Vast Pharmaceutical Potential. Molecules. 28(4):1862.
[14].
Laksemi, D.A.A.S, 2019,
Biological activity of Spondias pinnata: A review. Indonesia Journal of Biomedical Science, 13(2).
[15].
Sai K, Chhetri SBB, Devkota
SR, Khatri D. 2021, Evaluation of the Hypoglycemic Potential of Leaves Extract
of Spondias pinnata (L.f.) Kurz. from Nepal. Scientific World Journal. 3230351.
[16].
Rao BG.; Raju N J. 2010, Investigation
of Hepatoprotective Activity of Spondias pinnata,
Int J Pharma Sci Res., 1(3), 193-8.
[17].
Jain, Preeti, Khondker Rufaka
Hossain, Tamanna Rashid Mishu, and Hasan Mahmud Reza. 2013, Antioxidant and
Antibacterial Activities of Spondias pinnata
Kurz. Leaves. European Journal of
Medicinal Plants, 4 (2):183-95.
[18].
Ghate NB, Hazra B, Sarkar R,
Mandal N. 2014, In vitro anticancer activity of Spondias pinnata bark on human lung and breast carcinoma. Cytotechnology. 66(2):209-18.
[19].
Mondal, S., Bhar, K.,
Panigrahi, N., Mondal, P., Nayak, S., Barik, R. P., & Aravind, K. 2021, A Tangy
Twist Review on Hog-Plum: Spondias
pinnata (L.f.) Kurz. Journal of
Natural Remedies, 21(1), 1–25.
[20].
Chaudhuri D, Ghate NB, Singh
SS, Mandal N. 20155, Methyl gallate isolated from Spondias pinnata exhibits anticancer activity against human
glioblastoma by induction of apoptosis and sustained extracellular
signal-regulated kinase 1/2 activation. Pharmacogn
Mag. 11(42):269-76.
[21].
Patathananone S, Daduang J,
Koraneekij A, Li C. 2019, Tyrosinase Inhibitory Effect, Antioxidant and
Anticancer Activities of Bioactive Compounds in Ripe Hog Plum (Spondias
Pinnata) Fruit Extracts. Orient J Chem
35(3).
