Assessing the Utility of Pregnancy-Unique Quantification of Emesis Questionnaire's Score in Managing Women with Nausea and Vomiting of Pregnancy

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DOI: 10.21522/TIJPH.2013.SE.24.05.Art004

Authors : Deepthi P, Maghimaa M, Latha, S, Shanthi E

Abstract:

A lower quality of life and unfavorable pregnancy outcomes are linked to the severity of nausea and vomiting during pregnancy (NVP). This study used the Pregnancy-Unique Quantification of Emesis and Nausea (PUQE) scale to compare the severity of NVP with the various demographic and maternal parameters among pregnant women. To analyse the association of severity of nausea and vomitting using a modified PUQE scale with the various demographic and maternal characteristics This was a cross-sectional study conducted on 380 pregnant women who were receiving antenatal care at a tertiary health care centre between January 2023 and March 2024. The severity of NVP was evaluated by the PUQE scale which was later compared with the various maternal characteristics. Statistical analyses were performed to determine the risk factors associated with NVP. Gestational age was significantly associated with increasing NVP. Most of the subjects in the moderate (45.2%) and severe (47.7%) PUQE group were gravida 1 while 43.9% were gravida 2 in the mild group. PUQE scale can be used to assess the severity of NVP thus aiding the healthcare professionals in providing required treatment.

References:

[1].  Lacasse, A., Rey, E., Ferreira, E., Morin, C., & Bérard, A., 2008, Nausea and vomiting of pregnancy: What about quality of life?  BJOG: An International Journal of Obstetrics & Gynaecology115(12), 1484-1493.

[2].  Heitmann, K., Nordeng, H., Havnen, G. C., Solheimsnes, A., & Holst, L., 2017, The burden of nausea and vomiting during pregnancy: severe impacts on quality of life, daily life functioning and willingness to become pregnant again–results from a cross-sectional study. BMC Pregnancy and Childbirth17, 1-12.

[3].  Goodwin, T. M., & Ramin, S. M., 2015, Practice bulletin summary No. 153: Nausea and vomiting of pregnancy. Obstetrics and Gynecology126(3), 687-688.

[4].  Koren, G., Boskovic, R., Hard, M., Maltepe, C., Navioz, Y., & Einarson, A., 2002, Motherisk—PUQE (pregnancy-unique quantification of emesis and nausea) scoring system for nausea and vomiting of pregnancy. American Journal of Obstetrics and Gynecology186(5), S228-S231.

[5].  Fairweather, D. V., 1968, Nause and vomiting in pregnancy. American Journal of Obstetrics and Gynecology102(1), 135-175.

[6].  Verberg, M. F. G., Gillott, D. J., Al-Fardan, N., & Grudzinskas, J. G., 2005, Hyperemesis gravidarum, a literature review. Human Reproduction Update11(5), 527-539.

[7].  Vandraas, K. F., Vikanes, Å. V., Vangen, S., Magnus, P., Støer, N. C., & Grjibovski, A. M., 2013, Hyperemesis gravidarum and birth outcomes—a population‐based cohort study of 2.2 million births in the Norwegian Birth Registry. BJOG: An International Journal of Obstetrics & Gynaecology120(13), 1654-1660.

[8].  Birkeland, E., Stokke, G., Tangvik, R. J., Torkildsen, E. A., Boateng, J., Wollen, A. L., & Trovik, J., 2015, Norwegian PUQE (Pregnancy-Unique Quantification of Emesis and nausea) identifies patients with hyperemesis gravidarum and poor nutritional intake: a prospective cohort validation study. PloS One10(4), e0119962.

[9].  Choi, H. J., Bae, Y. J., Choi, J. S., Ahn, H. K., An, H. S., Yun, J. S., & Han, J. Y., 2018, Evaluation of nausea and vomiting in pregnancy using the Pregnancy-Unique Quantification of Emesis and Nausea scale in Korea. Obstetrics & Gynecology Science61(1), 30-37.

[10]. Kramer, J., Bowen, A., Stewart, N., & Muhajarine, N., 2013, Nausea and vomiting of pregnancy: prevalence, severity and relation to psychosocial health. MCN: The American Journal of Maternal/Child Nursing38(1), 21-27.

[11]. C Cicek, O. S. Y., & Demir, M. (2022). Evaluation of Nausea and Vomiting Severity in Pregnancies Conceived Through Assisted Reproduction. Gynecology Obstetrics & Reproductive Medicine28(1), 56-61.

[12]. Mitsuda, N., Eitoku, M., Yamasaki, K., Sakaguchi, M., Yasumitsu-Lovell, K., Maeda, N., & Suganuma, N., 2018, Nausea and vomiting during pregnancy associated with lower incidence of preterm births: the Japan Environment and Children’s Study (JECS). BMC Pregnancy and Childbirth18, 1-7.

[13]. Källén, B., Lundberg, G., & Åberg, A., 2003, Relationship between vitamin use, smoking, and nausea and vomiting of pregnancy. Acta Obstetricia et Gynecologica Scandinavica82(10), 916-920.

[14]. Bustos, M., Venkataramanan, R., & Caritis, S., 2017, Nausea and vomiting of pregnancy-What's new? Autonomic Neuroscience202, 62-72.s

[15]. Braunstein, G. D., & Hershman, J. M., 1976, Comparison of serum pituitary thyrotropin and chorionic gonadotropin concentrations throughout pregnancy. The Journal of Clinical Endocrinology & Metabolism42(6), 1123-1126.

[16]. Kaplan, P. B., Gücer, F., Sayin, N. C., Yüksel, M., Yüce, M. A., & Yardim, T., 2003, Maternal serum cytokine levels in women with hyperemesis gravidarum in the first trimester of pregnancy. Fertility and Sterility79(3), 498-502.

[17]. North, R. A., Whitehead, R., & Larkins, R. G., 1991, Stimulation by human chorionic gonadotropin of prostaglandin synthesis by early human placental tissue. The Journal of Clinical Endocrinology & Metabolism73(1), 60-70.

[18]. Davis, M. (2004). Nausea and vomiting of pregnancy: an evidence-based review. The Journal of Perinatal & Neonatal Nursing18(4), 312-328.

[19]. Niebyl, J. R., 2010, Nausea and vomiting in pregnancy. New England Journal of Medicine363(16), 1544-1550.

[20]. Roseboom, T. J., Ravelli, A. C., van der Post, J. A., & Painter, R. C., 2011, Maternal characteristics largely explain poor pregnancy outcome after hyperemesis gravidarum. European Journal of Obstetrics & Gynecology and Reproductive Biology156(1), 56-59.

[21]. Vikanes, Å., Skjærven, R., Grjibovski, A. M., Gunnes, N., Vangen, S., & Magnus, P. (2010). Recurrence of hyperemesis gravidarum across generations: population-based cohort study. Bmj340.

[22]. Trogstad, L. I., Stoltenberg, C., Magnus, P., Skjærven, R., & Irgens, L. M., 2005, Recurrence risk in hyperemesis gravidarum. BJOG: An International Journal of Obstetrics & Gynaecology112(12), 1641-1645.

[23]. Koren, G., Madjunkova, S., & Maltepe, C. (2014). The protective effects of nausea and vomiting of pregnancy against adverse fetal outcome—A systematic review. Reproductive Toxicology47, 77-80.

[24]. Chortatos, A., Haugen, M., Iversen, P. O., Vikanes, Å., Eberhard-Gran, M., Bjelland, E. K., & Veierød, M. B., 2015, Pregnancy complications and birth outcomes among women experiencing nausea only or nausea and vomiting during pregnancy in the Norwegian Mother and Child Cohort Study. BMC Pregnancy and Childbirth15, 1-11.

[25]. Bolin, M., Åkerud, H., Cnattingius, S., Stephansson, O., & Wikström, A. K., 2013, Hyperemesis gravidarum and risks of placental dysfunction disorders: a population‐based cohort study. BJOG: An International Journal of Obstetrics & Gynaecology120(5), 541-547.

[26]. Agampodi, S. B., Wickramasinghe, N. D., Horton, J., & Agampodi, T. C., 2013, Minor ailments in pregnancy are not a minor concern for pregnant women: a morbidity assessment survey in rural Sri Lanka. PloS One8(5), e64214.

[27]. Nurmi, M., Rautava, P., Gissler, M., Vahlberg, T., & Polo‐Kantola, P., 2020, Incidence and risk factors of hyperemesis gravidarum: a national register‐based study in Finland, 2005‐2017. Acta Obstetricia et Gynecologica Scandinavica99(8), 1003-1013.

[28]. Aishwarya, R., Ethirajan, S., 2022. Gestational Age at Booking for Antenatal Care in a Tertiary Healthcare Facility: A Glance. International Journal of Infertility & Fetal Medicine, 13(3), 91-95.

[29]. Rezvi, F. B., Duraisamy, R., Chaudhary, M., 2020. Oral Status of Pregnant Women-A Hospital Based Study. Int J Dentistry Oral Sci7(10), 881-887.

[30]. Ethirajan, S., Pritem, M. L., 2020. Study on knowledge and practice of periconceptional intake of folic acid among antenatal mothers at Saveetha Medical College Hospital, Tamil Nadu. Age, 20(25), 12-5.