The Antimicrobial Resistance Trend Pattern in A Subset Population of West Bengal

Download Article

DOI: 10.21522/TIJPH.2013.12.04.Art085

Authors : Shayeri Das, Sangita Agarwal, Dibya Das, Anirbandeep Bose

Abstract:

A deadly pandemic has threatened the world and is witnessing severe climate change. Constant environmental changes are leading to various viral/bacterial infections, which have increased the consumption of antibiotics. The rise in usage of antibiotics has increased significantly during the COVID-19 pandemic and post-COVID era. Generally, the most prescribed antibiotics fall under the broad-spectrum range as these work on many gram-positive and gram-negative disease-causing bacteria. There has been an increase in the accessibility and affordability of antibiotics among the population. The primordial factor for this is the over-the-counter buying of antibiotics followed by frequent usage of antibiotics. Patients often only finish part of the course of antibiotics. Frequent consumption of antibiotics and not completing the whole course of the antibiotics pose a severe and potentially irreversible threat to the healthy microbiome of the human intestine and a resistance pattern against the antibiotics. The study specifically focuses on understanding the antibiotic resistance pattern in the post-COVID scenario on the gut microbiome of the West Bengal population, making it particularly relevant to the local healthcare community. It underscores the urgent need for responsible antibiotic use, public awareness of the use of antibiotics, and antimicrobial resistance.

References:

[1]    Das, S, Agarwal, S., Bose, A., Das, D., 2024, Intestinal microbiome and antimicrobial resistivity: A study in recent times. Texila Internation Journal of Academic Research. DOI: 10.21522/TIJAR.2014.11.02. Art011.

[2]    Barron, M., 2022, The Gut Resistome and the Spread of Antimicrobial Resistance. American Society of Microbiology, June 2022. https://asm.org/Articles/2022/June/The-Gut-Resistome-and-the-Spread-of-Antimicrobial#. Accessed 24 Aug 2024.

[3]    Singh, S., Verma, N., Taneja, N., 2019, The human gut resistome: Current concepts & prospects. Indian Journal of Medical Research, 150(4): 345–358. DOI: 10.4103/ijmr.IJMR_1979_17.

[4]    Ezmed., Antibiotic Chart: Drug Names, Coverage and Mechanism of Action, Jan 2024, https://www.ezmedlearning.com/blog/antibiotic-classes-drug-names-coverage-mechanism-action.Accessed 24 Aug 2024.

[5]    Powell, A., Sheikh, Z., 2024, Antibiotics: Everything you should know. https://www.webmd.com/a-to-z-guides/what-are-antibiotics. Accessed on 24 Aug 2024.

[6]    React, SIDA, Uppsala University, 2024, How do antibiotics work? https://www.reactgroup.org/toolbox/understand/antibiotics/how-do-antibiotics-work/. Accessed 24 Aug 2024.

[7]    Infusion Services 2024; Cochise Oncology Article. https://cochiseoncology.com/infusion-services/. Accessed 24 Aug 2024.

[8]    Pascaul, C., Vergara, A., Vila, J., 2018, Intestinal microbiota and antibiotic resistance: Perspectives and solutions. Human Microbial Journal, vol. 9, 11-15. https://doi.org/10.1016/j.humic.2018.05.002.

[9]    Yang, L., Bajinka, O., Jarju, P.O. et al. The varying effects of antibiotics on gut microbiota. AMB Expr 11, 116, 2021. https://doi.org/10.1186/s13568-021-01274-w

[10] Matzaras, R., Nikopoulou, A., Protonotariou, E., Christaki, E., Gut Microbiota Modulation and Prevention of Dysbiosis as an Alternative Approach to Antimicrobial Resistance: A Narrative Review. Yale J Biol Med. 2022 Dec 22;95(4):479-494. PMID: 36568836; PMCID: PMC9765331.

[11] Aliouche, H., 2022, The Effect of Antibiotics on Gut Microbiome. News Medical Life Sciences. https://www.news-medical.net/health/. Accessed 24 Aug 2024.

[12] WHO Report 2020 Antibiotic Resistance. https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance. Accessed 24 Aug 2024.

[13] [Porter, Gerard & Kotwani, Anita & Bhullar, Lovleen & Joshi, Jyoti. 2021, Over-the-counter sales of antibiotics for human use in India: The challenges and opportunities for regulation. Medical Law International. 21. 147-173. DOI: 10.1177/09685332211020786.

[14] Kotwani, A., Joshi, J., Lamkang, A. S., Over-the-Counter Sale of Antibiotics in India: A Qualitative Study of Providers' Perspectives across Two States. Antibiotics (Basel). 2021 Sep 17, 10(9), 1123. doi: 10.3390/antibiotics10091123. PMID: 34572705; PMCID: PMC8472180.

[15] Ghafur, Abdul. 2010. An obituary - On the death of antibiotics. The Journal of the Association of Physicians of India. 58. 143-4.

[16] Salunkhe, S.D. & Pandit, Vijaya & Dawane, Jayshree & Sarda, Kushal & More, C.S. 2013, Study of over-the-counter sale of antimicrobials in pharmacy outlets in Pune, India: A cross-sectional study. International Journal of Pharma and Bio Sciences. 4. P616-P622.

[17] WHO Factsheet, 2023 on Antimicrobial Resistance. https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance#. Accessed 24 Aug 2024.