Abstract:

Dengue, a significant viral disease spread by mosquitoes, is causing an increasing death rate due to inadequate treatments and preventative measures. However, there has been substantial advancement in the investigation of natural and traditional herbal remedies. Tinospora cordifolia has been extensively researched for its ability to treat dengue fever. This research aims to assess the current information on the use of T. cordifolia in treating dengue, emphasizing its clinical effectiveness, phytochemistry, and antiviral properties. The research methodology included an extensive examination of the literature on T. cordifolia's anti-dengue attributes in different databases utilizing appropriate keywords. Discoveries validate the effectiveness of T. cordifolia in fighting dengue by easing cytokine storms, decreasing vascular leakage, and blocking key viral proteins. Substances like berberine and magnoflorine obtained from the plant exhibit potential in this aspect. The research not only highlights but also underscores the significant potential of T. cordifolia as a beneficial treatment option for dengue, but additional computational and clinical studies are necessary to create effective and safe anti-dengue drugs. Moreover, it is crucial to have a more thorough comprehension of T. cordifolia's antiviral method in combating dengue virus infection.

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