Assessment of Knowledge of DNA among Dental Students in Chennai, India
Abstract:
Although there have been
several recent advances in genomic technology over the past two decades, little
to no change has occurred in the incorporation of genetics in dental school
curricula. Also, there are only a limited number of studies that have reported
the knowledge and awareness of genetics in dental professionals. With the
available information, the present study was conducted to analyze the knowledge
of DNA among dental students. This cross-sectional study was conducted among
302 dental students from various Dental Colleges across Chennai to assess the
knowledge of DNA among dental students. It was done using a questionnaire
survey from May 2021 to June 2021comprising of 14 questions that were validated
owing to the pandemic situation, the survey was conducted online using Google
Forms Student T-test was planned to statistically analyze the result. The mean
percentage of correct responses from students of various academic years was
calculated and it was observed that interns had better knowledge and interest
in genetics (81.39%), followed by final-year students (80.9%), first-year
students 75%, third-year students (74.76%) and second-year students (73.07%).
Considering gender, females (77.21%) had better knowledge of genetics than
males (75.2%). The results were not statistically significant. The basic
concepts of genetics and applications of genetics have to be incorporated into the
dental curriculum. This can also be accomplished by conducting educational
programs during the study and continuing dental educational programs after they
complete their course.
References:
[1]. Maffeo, C., Yoo, J., Comer, J.,
Wells, D. B., Luan, B., Aksimentiev, A., 2014, Close encounters with DNA. J
Phys Condens Matter,
26(41), 413101. doi: 10.1088/0953-8984/26/41/413101.
[2]. Jaekel,
A., Lill, P., Whitelam, S., & Saccà, B., 2020. Insights into the Structure
and Energy of DNA Nanoassemblies. Molecules (Basel, Switzerland), 25(23), 5466. https://doi.org/10.3390/molecules25235466.
[3]. .
Watson, J.D., Crick, F.H.C., 1953, Molecular Structure of Nucleic Acids: A
Structure for Deoxyribose Nucleic Acid. Nature, 171, 737–738. doi: 10.1038/171737a0.
[4]. Watson
J.D., Crick, F.H.C, 1953, Genetical Implications of the Structure of
Deoxyribonucleic Acid. Nature,
171,964–967. doi: 10.1038/171964b0.
[5].
Mc Gruder, Carla., Evaluation of current knowledge of genetics
among dental students, residents and dental hygiene students 2015, The University
of Texas MD Anderson Cancer Center uthealth graduate school of biomedical
sciences dissertations and theses (Open Access). 579. https://digitalcommons.library.tmc.edu/utgsbs_dissertations/579.
[6].
Baars,
M. J., Henneman, L., Ten, Kate, L. P., 2005, Deficiency of knowledge of
genetics and genetic tests among general practitioners, gynaecologists, and
pediatricians: a global problem. Genet Med., 7(9), 605-10. doi:
10.1097/01.gim.0000182895.28432.c7. PMID: 16301861.
[7].
Slavkin, Harold, 2014, Revising the scope of practice for oral
health professionals: Enter genomics. Journal of the American Dental
Association, 1939 (145), 228-230. 10.14219/jada.2014.11.
[8].
Loos, B. G., & Van Dyke, T. E., 2020, The role of inflammation
and genetics in periodontal disease. Periodontology 2000, 83(1), 26–39. https://doi.org/10.1111/prd.12297.
[9].
Shaffer, J.R., Xiaojing
Wang, Daniel, W. M., Robert, J. W., Richard, C., and Mary L. M., 2015, Genetic
susceptibility to dental caries differs between the Sexes: A family-based
study. Caries Research, 49(2),133–140. doi:10.1159/000369103.
[10].
De Coster, P. J., Marks, L. A., Martens, L. C., & Huysseune,
A. 2009, Dental agenesis: genetic and clinical perspectives. Journal of oral
pathology & medicine: official publication of the International Association
of Oral Pathologists and the American Academy of Oral Pathology, 38(1),
1–17. https://doi.org/10.1111/j.1600-0714.2008.00699.x.
[11].
Alade, A., Awotoye, W., & Butali, A.,2022, Genetic and
epigenetic studies in non-syndromic oral clefts. Oral diseases, 28(5),
1339–1350. https://doi.org/10.1111/odi.14146.
[12]. Balachander, K.,
and Paramasivam. A.,2023, The implication of mitochondrial DNA mutation
and dysfunction in periodontal diseases. J Indian Soc Periodontol,
27(2), 126–130.
[13].
Abdul, N.S., Shenoy, M., Reddy, N.R. et al. 2024, Gene sequencing
applications to combat oral-cavity related disorders: a systematic review with
meta-analysis. BMC Oral Health, 24, 103, https://doi.org/10.1186/s12903-023-03541-7.
[14].
Rajasekar, A., Balu, P., Kumar, S. R., & Varghese, S. S.,
2023, Comparison of Microbial Composition of Natural Teeth and Implants by 16S
rRNA Gene Sequencing. Journal of Long-Term Effects of Medical Implants,
33(3), 1–8. https://doi.org/10.1615/JLongTermEffMedImplants.2022044519.
[15].
Sujatha, G., Priya, V. V., Varadarajan, S., et al., 2022, A
Bibliometric Analysis of the Published Literature Related to Toothbrush as a
Source of DNA. World J Dentistry, 13(S-1), S87–S95.
[16].
Johnson,
L., Genco, R. J., Damsky, C., Haden, N. K., Hart, S., Hart, T. C., Shuler, C. F.,
Tabak, L. A., Tedesco, L. A., 2008, Genetics and its implications for clinical
dental practice and education: Report of panel 3 of the Macy study. J Dent
Educ, 72(2 Suppl):86-94. PMID: 18250384.
[17].
Jorgenson, R. J.,1980, The role of the dentist in
genetic counseling. Birth Defects Orig Artic
Ser, 16, 139–45.
[18].
D, Merdad L., Ramadan, E., 2016, Knowledge of Genetics and
Attitudes toward Genetic Testing among College Students in Saudi Arabia. Public
Health Genomics,19, 260-268. doi: 10.1159/000446511.
[19].
Keerthika, S.,
Vishnupriya, V., Gayathri, R., Selvaraj, J, 2019, Knowledge,
attitude, and awareness of DNA fingerprinting among college students Drug
Invention Today, 2378-2383.
[20].
Gupta, R., Chandra Shekar, B. R., Goel, P.,
Hongal, S., Ganavadiya, R., 2019, Role of dentist in genetic counseling: A
critical appraisal of the current practices and future requirements in Indian
scenario. Dent Res J (Isfahan), 16(3), 131-138.
[21].
Johnson, L., Genco, R. J., Damsky, C., Haden, N. K., Hart, S.,
Hart, T. C., Shuler, C. F., Tabak, L. A., tedesco, L. A., Behnke, A. R.,
Hassell, T. M., 2004, Need for genetics education in U.S. Dental and dental
hygiene programs. J Dent Educ, 68, 819–22.
[22].
Behnke, A. R., Hassell, T. M., 2004, Need for
genetics education in U.S. Dental and dental hygiene programs. J Dent Educ, 68, 819–22.
[23].
Dudlicek, L. L., Gettig, E. A., Etzel, K.R., Hart,
T. C., 2004, Status of genetics education in U.S. Dental schools. J Dent Educ, 68:809–18.
Genetics and its implications for clinical dental practice and education: Report
of panel 3 of the Macy study. J Dent Educ., 72(2 Suppl, 86-94.
[24]. Collins, F., Tabak, L., 2004, A call for increased education in
genetics for dental health professionals. J Dent Educ., 68, 807–8.