Nano-materials in Drug Delivery Systems for Oral Cancer Treatment

Download Article

DOI: 10.21522/TIJPH.2013.12.03.Art052

Authors : Periasamy Anbu, Indu Vadhana T. M, Shanmuga Sundar Saravanabhavan, Selvan Kumar T.

Abstract:

Oral cancer is a serious health concern requiring target-specific treatment strategies due to its high rates of morbidity and mortality. Early detection of cancer cells considerably improves prognosis and treatment outcomes. Recently, nanomaterials have opened a world of intriguing new possibilities for cancer diagnosis and therapy by providing creative ways to enhance patients' quality of life. Furthermore, modified nanoparticles use specially designed moieties to target cancer cells more precisely. Drug delivery methods could reduce side effects and significantly improve oral cancer treatment efficacy. In addition, polymer-based drug delivery methods are designed to release drugs gradually and in a controlled way. In addition, the combination therapy with a drug delivery system leads to a synergetic effect are also discussed.

References:

[1].   Borse, V., Konwar, A.N., Buragohain, P., 2020. Oral cancer diagnosis and perspectives in India. Sens Int. 1, 100046.

[2].   Liang, K.H., Lin, Y.Y., Chiang, S.H., Tsai, E.T., Lo, W..L, Wang, C.L., Wang, T.Y., Sun, Y.C., Kao, S.Y., Wu, C.H., Hung, K.F., 2021. Recent progress of biomarkers in oral cancers. J Chinese Med Assoc. 84, 987-992.

[3].   Alam, M.K., Alqhtani, N.R., Alnufaiy, B., et al. 2024. A systematic review and meta-analysis of the impact of resveratrol on oral cancer: potential therapeutic implications. BMC Oral Health. 24, 412.

[4].   Satapathy, P., Khatib, M.N., Gaidhane, S., Zahiruddin, Q.S., et al. 2024. Prevalence of human papillomavirus in head and neck cancer patients in India: a systematic review and meta-analysis. BMC Infect Dis. 24, 516.

[5].   Arshad, S., Hussain, S.F.J., Jayaram, S., Veeraraghavan, V.P., Karobari, M.I,. 2024. Perspective on enhancing quality of life in oral cancer patients: Integrative approaches and comprehensive care. Oral Oncol Report. 11, 100633.

[6].   Mustafa, A., Indiran, M.A., Ramalingam, K., Perumal, E., Shanmugham, R., Karobari, M.I., 2024. Anticancer potential of thiocolchicoside and lauric acid loaded chitosan nanogel against oral cancer cell lines: a comprehensive study. Sci Rep. 14, 9270. 

[7].   Hosomi, Y., Morita, S., Sugawara, S., Kato, T., Fukuhara, T., Gemma, A., Takahashi, K., Fujita, Y., Harada, T., Minato, K., Takamura, K., Hagiwara, K., Kobayashi, K., Nukiwa, T., Inoue, A., 2020. North-East japan study group. gefitinib alone versus gefitinib plus chemotherapy for non-Small-cell lung cancer with mutated epidermal growth factor receptor: NEJ009 Study. J Clin Oncol. 38, 115-123.

[8].   Dristant, U., Mukherjee, K., Saha, S., Maity, D., 2023. An overview of polymeric nanoparticles-based drug delivery system in cancer treatment. Technol. Cancer Res Treatment. 22:1-23.

[9].   Salari, N., Faraji, F., Torghabeh, F.M., Faraji, F., Mansouri, K., Abam, F., Shohaimi, S., Akbari, H., Mohammadi, M., 2022. Polymer-based drug delivery systems for anticancer drugs: A systematic review. Cancer Treatment and Res Communication. 32, 100605.

[10].  Beaux, M.F., McIlroy, D.N., Gustin, K.E., 2008. Utilization of solid nanomaterials for drug delivery. Expert Opinion Drug Deliv. 5, 725-735.

[11].  Dang, Y., Guan, J., 2020. Nanoparticle-based drug delivery systems for cancer therapy. Smart Mat Med. 1, 10-19.

[12].  Saha, C., Kaushik, A., Das, A., Pal, S., Majumder, D., 2016. Anthracycline drugs on modified surface of quercetin-loaded polymer nanoparticles: A dual drug delivery model for cancer treatment. PLoS One 2016;11:e0155710.

[13].  Beach., M.A., Nayanathara, U., Gao, Y., Zhang, C., Xiong, Y., Wang, Y., Such, G.K., 2024. Polymeric nanoparticles for drug delivery. Chem Rev. 124, 5505-5616.

[14].  Gu, Z., Da Silva, C.G., Van der Maaden, K., Ossendorp, F., Cruz, L.J., 2020. Liposome-Based Drug Delivery Systems in Cancer Immunotherapy. Pharmaceutics.12, 1054.

[15].  Ghanbarikondori, P., Aliakbari, R.B.S., Saberian, E. et al. 2024. Enhancing Cisplatin Delivery via Liposomal Nanoparticles for Oral Cancer Treatment. Ind J Clin Biochem.

[16].  Wang, J., Gong, J., Wei, Z., 2022. Strategies for Liposome Drug Delivery Systems to Improve Tumor Treatment Efficacy. AAPS PharmSciTech  23, 27.

[17].  Duarte, D., Vale, N., 2022. Evaluation of synergism in drug combinations and reference models for future orientations in oncology. Curr Res Pharmacol Drug Discov.3, 100110.

[18].  Gavas, S., Quazi, S., Karpiński, T.M., 2021. Nanoparticles for Cancer Therapy: Current Progress and Challenges. Nanoscale Res Lett. 16, 173.

[19].  Cheng, X., Xie, Q., Sun, Y., 2023. Advances in nanomaterial-based targeted drug delivery systems. Front Bioeng Biotechnol. 11, 1177151.

[20].  Krzyszczyk, P., Acevedo, A., Davidoff E.J, Timmins, L.M., Marrero-Berrios, I., Patel, M., White, C., Lowe, C., Sherba, J.J., Hartmanshenn, C., O'Neill, K.M., Balter, M.L., Fritz, Z.R., Androulakis, I.P., Schloss, R.S., Yarmush, M.L., 2018. The growing role of precision and personalized medicine for cancer treatment. Technology (Singap World Sci), 6, 79-100.