Transformative Nano-Drug Delivery Strategies: Addressing Challenges in Modern Therapeutics
Abstract:
The conventional methods of drug
delivery, primarily oral and injectable routes, have encountered limitations in
effectively administering new drugs. These limitations arise particularly with
drugs such as proteins and nucleic acids, where traditional routes may not be
optimal for therapeutic efficacy. Novel biological medications necessitate
innovative delivery strategies to mitigate adverse effects and enhance patient
compliance. Nanometer-sized drug particles present unique characteristics that
offer potential improvements in various dosage formats. Within this size range,
particles exhibit resistance to settling, increased saturation solubility,
rapid dissolution, and enhanced adherence to biological surfaces. Consequently,
these properties facilitate a quicker onset of therapeutic action and improved
bioavailability. The emergence of nanotechnology provides scientists with a
versatile tool to address both traditional and innovative drug delivery
challenges. By leveraging nanotechnology, researchers explore new avenues for
drug delivery, striving to optimize therapeutic outcomes while minimizing
adverse effects. This review underscores the transformative potential of nano-drug
delivery systems in advancing pharmaceutical sciences and enhancing patient
care.
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