Abstract:

The word atherosclerosis consists of two parts: atherosis (accumulation of fats accompanied by several macrophages) and sclerosis (fibrosis layer comprising smooth muscle cells. The presence of hyperlipaemia is the major risk issue factor for coronary artery disease. In 2016 advances in atherosclerosis research were focused on the discovery and validation of newly targeted genetics and mechanistic connection to atherothrombotic heart diseases. The Survey on awareness about the risk factors and complications of liver cirrhosis among college students was conducted using a Google form link. We have distributed our survey among 100 college students. Pie charts and Bar diagrams were used to represent output variables. Results showed that the knowledge of cardiovascular 54.00 % said No and 46.00 % said yes. Stroke caused due to lack of blood supply to 44.00 % said heart, 50.00 % said brain, and 6.00 % said I don’t know. These findings conclude that the majority of the population is unaware of the risk factors such as obesity, LDL, and family history, which lead to the development of atherosclerosis, but only a few populations are aware of stress, smoking, coronary heart attack, cholesterol, sleep apnea, HDL, work pressure, physical activity, heart disease, and coronary disease that leads to atherosclerosis.

References:

[1] Rafieian-Kopaei, M., Setorki, M., Doudi, M., Baradaran, A., Nasri, H., 2014, Atherosclerosis: Process, Indicators, Risk Factors and New Hopes. Int J Prev Med. 5(8), 927.

[2] Wilson, W. H., Tang, S .L. H., 2017, Advances In New Therapeutic Targets For Atherosclerosis. Nat Rev Cardiol. 14(2), 71.

[3] Babu, S., Jayaraman, S., 2020, An Update on β-sitosterol: A Potential Herbal Nutraceutical For Diabetic Management, Biomed Pharmacother, 131, 110702.

[4] Yasothkumar, D., Jayaraman, S., Ramalingam, K., Ramani, P., 2023. In vitro Anti-Inflammatory and Antioxidant Activity of Seed Ethanolic Extract of Pongamia pinnata. Biomedical and Pharmacology Journal, 16(4).

[5] Gianturco, L., 2018, Atherosclerosis: Yesterday, Today and Tomorrow. BoD – Books on Demand, 128 p.

[6] Luepker, R. V., Evans, A., McKeigue, P., Srinath, Reddy, K., 2004, Cardiovascular Survey Methods. World Health Organization, 185 p.

[7] Insull, W, Jr., 2009, The Pathology of Atherosclerosis: Plaque Development and Plaque Responses To Medical Treatment. Am J Med. 122(1), S3–14.

[8] Dutta, P., Courties, G., Wei, Y., Leuschner, F., Gorbatov, R., Robbins C, et al. 2012, Myocardial Infarction Accelerates Atherosclerosis. Nature. 487(7407), 325.

[9] Singh, P., Goncalves, I., Tengryd, C., Nitulescu, M., Persson, A.F., To, F., et al. 2021, Correction to: Reduced oxidized LDL in T2D Plaques is Associated with A Greater Statin Usage but not with Future Cardiovascular Events. Cardiovasc Diabetol. 20(1), 61.

[10]   Pastori, D., Sciacqua, A., Marcucci, R., Del Ben, M., Baratta, F., Violi, F., et al. 2021. Non-alcoholic fatty liver disease (nafld), metabolic syndrome and cardiovascular events in atrial fibrillation. A prospective multicenter cohort study. Intern Emerg Med.  16(8), 2063-2068.

[11]   Kamalli, M.K., Kavitha, S., Sangeetha, A., Vishnupriya, V., Gayathri, R., 2020, Awareness on Cardiovascular Risk Factors Among Working Women - A Questionnaire Survey. Vol. 11, International Journal of Research in Pharmaceutical Sciences. 11, 616-25.

[12]   Sathya, S., Ragul, V., Veeraraghavan, V.P., Singh, L., Niyas Ahamed, M.I., 2020, An in vitro study on hexavalent chromium [Cr(VI)] remediation using iron oxide nanoparticles-based beads, Environmental Nanotechnology, Monitoring & Management, 2020, 14, 100333.

[13]   Veeraraghavan, V. P., Hussain, S., Balakrishna, J. P., Dhawale, L., Kullappan, M., Ambrose, J. M, et al., 2021, A Comprehensive and Critical Review on Ethnopharmacological Importance of Desert Truffles: Terfezia claveryi, Terfezia boudieri, and Tirmania nivea, Food Reviews International, 1–20.

[14]   Libby, P., 2021, Atherosclerosis: from biology to therapeutics. bioRxiv. https://doi.org/10.1101/2021.05.06.443593.

[15]   Kotseva, K., De Backer, G., De Bacquer, D., Rydén, L., Hoes, A., Grobbee, D., . & Wood, D. (2019). Lifestyle and impact on cardiovascular risk factor control in coronary patients across 27 countries: Results from the European Society of Cardiology ESC-EORP EUROASPIRE V registry. European Journal of Preventive Cardiology, 26(8), 824-835.

[16]   Rohatgi, A., Khera, A., Berry, J. D., Givens, E. G., Ayers, C. R., Wedin, K. E., de Lemos, J.A., 2014, HDL Cholesterol Efflux Capacity And Incident Cardiovascular Events. New England Journal of Medicine, 371(25), 2383-2393.

[17]   Huang, T. T-K., Huang, T. T., Shimel, A., Lee, R. E., Delancey, W., Strother, M. L., 2007, Metabolic Risks among College Students: Prevalence and Gender Differences. Metabolic Syndrome and Related Disorders. 5, 365–72.

[18]   Burke, J.D., Reilly, R.A., Morrell, J.S., Lofgren, I.E., 2009, The University of New Hampshire’s Young Adult Health Risk Screening Initiative. Journal of the American Dietetic Association. 109, 1751–8.

[19]   Jagadheeswari, R., Vishnu Priya, V., Gayathri, R., 2020, Awareness of Vitamin-C Rich Foods Among South Indian Population: A Survey, Journal of Research in Medical and Dental Science, 8(7), 330-338.

[20]   Ojastha, B.L., Selvaraj, J., Kavitha, S., Veeraraghavan Vishnu Priya., Gayathri R., 2023, Effect Of Argyreia Nervosa On The Expression Of Growth Factor Signaling In The Skeletal Muscle of Streptozotocin-Induced Experimental Diabetic Rats. Journal of Namibian Studies: History Politics Culture, 33, 5942-5950. https://doi.org/10.59670/jns.v33i.4474

[21]   Vishaka, S., Sridevi, G., Selvaraj, J., 2022, An in vitro analysis on the antioxidant and anti-diabetic properties of Kaempferia galanga rhizome using different solvent systems. Journal of Advanced Pharmaceutical Technology & Research, 13(2), S505–9.

[22]   Bhalge,U., Gaikwad, B., Kulkarni, P., Takalkar, A.A., Bhise, M.D., 2018. Assessment of awareness about cardiovascular diseases risk factors amongst first year medical students [Internet]. International Journal Of Community Medicine And Public Health. 6, 105.

[23]   Karthik, E.V.G., Priya, V.V., Gayathri. R., 2021. Dhanraj Ganapathy. Health Benefits Of Annona Muricata-A Review. International Journal of Oral Science, 8(7), 2965–7.

[24]   Mithil Vora, Vishnu Priya, V., Selvaraj,J., Gayathri, R., Kavitha, S., 2021, Effect of Lupeol on proinflammatory Markers in Adipose Tissue of High-Fat Diet and Sucrose Induced Type-2 Diabetic Rats. Journal of Research in Medical and Dental Science, 9(10),116-121.

[25]   Sadasivam, P., Ganapathy, D.M., Sasanka, L.K.,2023, Assessment of Depressive Behaviour among the Undergraduate Dental students-A Survey. Turkish Journal of Physiotherapy and Rehabilitation, 32, 2.

[26]   Ealla KKR, Veeraraghavan VP, Ravula NR, Durga CS, Ramani P, Sahu V, Poola PK, Patil S, Panta P (2022) Silk Hydrogel for Tissue Engineering: A Review. J Contemp Dent Pract 23:467–477

[27]   Patil S, Sujatha G, Varadarajan S, Priya VV (2022) A bibliometric analysis of the published literature related to toothbrush as a source of DNA. World J Dent 13:S87–S95

[28]   Ganesan A, Muthukrishnan A, Veeraraghavan V (2021) Effectiveness of Salivary Glucose in Diagnosing Gestational Diabetes Mellitus. Contemp Clin Dent 12:294–300

[29]   Priya DV, (2020) Knowledge and awareness on HIV/AIDS among college students in A university hospital setting. Int J Dent Oral Sci 1182–1186

[30]   Prakash S, Balaji JN, Veeraraghavan VP, Mohan SK (2022) Telehealth: Is It a Post-COVID Reality in Early Diagnosis of Oral Cancer? J Contemp Dent Pract 23:1181–1182