Estimating the Biological Age and the Magnitude of Lifestyle Determinants of Ageing among Nigerian Adults

Download Article

DOI: 10.21522/TIJPH.2013.10.04.Art009

Authors : Abiodun Bamidele Adelowo, Olaiya Paul Abiodun

Abstract:

Considering the various limitations of using chronological age, biological age estimation is becoming increasingly recognized as one of the novel public health and clinical strategies for preventing and controlling the rising global prevalence of noncommunicable diseases (NCDs) and for achieving healthy ageing. The objectives of this study are to estimate the biological age and compare it to the chronological age of Nigerian adults. Also, to score the magnitude of some of the lifestyle determinants of biological age among the study population. This cross-sectional study uses simple random sampling technique to select 82 Nigerian adults for the study, while standardized instruments were used to collect data. The P value for the study was set at 0.05 level of significance. The result of the study noticed poor mean Mediterranean Diet Adherence (MDAQ) score of 7.0 ± 2.28 and mean International Physical Activity (IPAQ) score of 1.3 ± 0.51. There was also suboptimal mean Pittsburgh Sleep Quality Index (PSQI) score of 5.9 ± 3.01, mean Perceive Stress Scale-4 (PSS-4) score of 6.3 ± 2.79, and mean Social Connectedness Scale (SCS) score of 15.2 ± 4.13. Furthermore, the estimated biological age of the respondents (45.9 years, ±10.31), was higher than their chronological age (43.2 years, ±8.92). The study concluded that the magnitudes of the lifestyle determinants of ageing are high enough to result in accelerated biological ageing among the study population. Such development, if not mitigated, may result in a significant increase in the prevalence of NCDs and premature deaths in the near future.

Keywords: Accelerated Ageing, Biological Age, Chronological Age, Lifestyle determinants of ageing, Health Promotion Intervention.

References:

[1] Pathath A.W., 2017, Theories of Aging. International Journal of Indian Psychology, 4 (3), 15 – 22. https://DOI:10.25215/0403.142.

[2] Jia L., Zhang W., and Chen X., 2017, Common methods of biological age estimation. Clinical Interventions in Aging, 12, 759–772.

[3] Cavallasca J., 2017, Measuring aging: what is your physiological age? Date of access: 2/4/2021. http://www.longlonglife.org/en/transhumanism-longevity/aging/measure-of-aging/measuring-aging-physiological-age/.

[4] Jiang S., and Guo Y., 2020, Epigenetic Clock: DNA Methylation in Aging. Stem Cells International, 2020, 1 – 9. https://doi.org/10.1155/2020/1047896.

[5] Kim S., and Jazwinski S.M., 2015, Quantitative measures of healthy aging and biological age. Healthy Aging Res., 4, 1 – 25. http://doi:10.12715/har.2015.4.26.

[6] Rollandi G.A., Chiesa A., Sacchi N., Castagnetta M., Puntoni M., Amaro A., et al., 2019, Biological Age versus Chronological Age in the Prevention of Age Associated Diseases, OBM Geriatrics, 3(2), 1 – 14, https://doi:10.21926/obm.geriatr.1902051.

[7] Kim S., Myers L., Wyckoff J., Cherry K.E., and Jazwinski S.M., 2017, The frailty index outperforms DNA methylation age and its derivatives as an indicator of biological age. GeroScience, 39, 83 – 92. https://DOI10.1007/s11357-017-9960-3.

[8] Waters D., 2020, This biological age calculator shows how old your body is. Date of access: 4/6/2021. https://www.womanandhome.com/health-and-wellbeing/biological-age-calculator-20430/.

[9] Kresovich J.K., Xu Z., O’Brien K.M., Weinberg C.R., Sandler D.P., and Taylor J.A., 2019, Methylation-Based Biological Age and Breast Cancer Risk. J Natl Cancer Inst., 1, 111(10), 1051-58. https://doi:10.1093/jnci/djz020.

[10] Waters D., 2020, This biological age calculator shows how old your body is. Date of access: 4/6/2021. https://www.womanandhome.com/health-and-wellbeing/biological-age-calculator-20430/.

[11] Federal Ministry of Health of Nigeria, 2015, National Strategic Plan of Action on Prevention and Control of Non-Communicable Diseases. Date of access: 21/7/2021 https://www.medbox.org/document/nigeria-national-strategic-plan-of-action-on-prevention-and-control-of-non-communicable-diseases#GO.

[12] World Health Organization, 2018, Non-communicable Diseases Country profiles 2018. Date of access: 21/7/2022. https://www.who.int/nmh/publications/ncd-profiles-2018/en/.

[13] Thompson A.E., Anisimowicz Y., Miedema B., Hogg W., Wodchis W.P., & Aubrey-Bassler K., 2016, The influence of gender and other patient characteristics on health care-seeking behaviour: a QUALICOPC study, BMC Family Practice, 17, 38. https://DOI:10.1186/s12875-016-0440-0.

[14] Lim M.T., Lim Y.M.F., Tong S.F., and Sivasampu S., 2019, Age, sex and primary care setting differences in patients’ perception of community healthcare seeking behaviour towards health services, PLoS ONE 14(10), e0224260. https://doi.org/10.1371/journal.pone.0224260.

[15] de Wit J.B.F., Peeters M., and Koning I., 2022, Risk Behaviour and Health Outcomes of Adolescents and Young Adults. Date of access: 20/7/2022. https://www.frontiersin.org/research-topics/5907/risk-behaviour-and-health-outcomes-of-adolescents-and-young-adults.

[16] Hilz R., & Wagner M., 2018, Marital Status, Partnership and Health Behaviour: Findings from the German Ageing Survey (DEAS). Comparative Population Studies, 43, 65-98. https://DOI:10.12765/CPoS-2018-08en.

[17] Fuchs M., 2021, Want to add healthy years to your life? Here’s what new longevity research says. Date of access: 9/8/2021. https://www.washingtonpost.com/lifestyle/wellness/longevity-research-diet-exercise-tips/2021/10/10/edb5cdc2-2856-11ec-9de8-156fed3e81bf_story.html

[18] Abuduxike G., Aşut Ö, Vaizoğlu S.A., and Cali S., 2020, Health-Seeking Behaviors and its Determinants: A Facility-Based Cross-Sectional Study in the Turkish Republic of Northern Cyprus. Int J Health Policy Manag, x(x), 1–10. https://Doi:10.15171/ijhpm.2019.106.

[19] International Diabetes Federation, 2021, IDF Diabetes Atlas 10th edition. Date of access: 20/7/2022. https://diabetesatlas.org/idfawp/resource-files/2021/07/IDF_Atlas_10th_Edition_2021.pdf.

[20] Federal Ministry of Health of Nigeria, 2021, National Guideline on The Prevention, Control and Management of Diabetes Mellitus. Date of access: 21/7/2022. https://www.health.gov.ng/doc/National%20Guideline%20for%20the%20prevention,%20control%20and%20management%20of%20Diabetes%20Mellitus%20in%20Nigeria%20(3).pdf.

[21] World Health Organization, 2011, Global Status Report on Non-Communicable Diseases 2010. Date of access: 21/7/2022. https://apps.who.int/iris/bitstream/handle/10665/44579/9789240686458_eng.pdf?sequence=1&isAllowed=y.

[22] Furman D., Campisi J., Verdin E., Carrera-Bastos P., Targ S., Franceschi C., et al., 2019, Chronic inflammation in the etiology of disease across the life span. Nature Medicine, 25, 1822 – 1832. https://doi.org/10.1038/s41591-019-0675-0.

[23] Akarolo-Anthony S.N., Willett W.C., Spiegelman D., and Adebamowo C.A. Obesity epidemic has emerged among Nigerians. BMC Public Health 2014, 14:455. http://www.biomedcentral.com/1471-2458/14/455.

[24] Chukwuonye I.I., Chuku A., John C., Ohagwu K.A., Imoh M.E., Isa S.E., et al., 2013, Prevalence of overweight and obesity in adult Nigerians – a systematic review. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 6, 43–47.

[25] Södergren M., 2013, Lifestyle predictors of healthy ageing in men. Maturitas., 75(2), 113-7. https://DOI:10.1016/j.maturitas.2013.02.011.

[26] Adelowo A.B., 2021, Analyzing the Magnitude of Global Epidemiological Transition in Sub-Saharan Africa: A Need to Review the Current Healthcare Management Approach. Texila International Journal of Public Health, 9 (3); 204 – 212. https://DOI:10.21522/TIJPH.2013.09.03.Art018.

[27] Adelowo A.B., 2022, A Scoping Review of Cardio-Metabolic Syndrome: A Critical Step in Mitigating the Rising Global Burden of Cardiovascular Diseases and Diabetes Mellitus. Int J Diabetes Metab Disord, 7(1): 80-86. https://doi.org/10.33140/IJDMD.07.01.13.

[28] Federal Ministry of Health of Nigeria, 2014, National Nutritional Guideline on Non-Communicable Disease Prevention, Control and Management. Date of access: 13/12/2016. http://www.health.gov.ng/doc/NutritionalGuideline.pdf.

[29] Agu AU, Esom EA, Chime SC, Anyaeji PS, Anyanwu GE, and Obikili EN., 2021, Impact of sleep patterns on the academic performance of medical students of College of Medicine, University of Nigeria. Int J Med Health Dev, 26, 31-6.

[30] Onoh I., 2017, World Sleep Day: How sleep deprivation threatens Lagosians’ wellbeing – Expert. Date of access: 4/8/2022. https://www.environewsnigeria.com/world-sleep-day-sleep-deprivation-threatens-lagosians-wellbeing-expert/.

[31] Adelowo A.B, 2020, Sleep: An Insight into the Neglected Component of a Healthy Lifestyle. Nigerian School of Health Journal, 32 (1), 75-87.

[32] Wilson D., Driller M., Johnston B., and Gill N., 2021, The effectiveness of a 17-week lifestyle intervention on health behaviors among airline pilots during COVID-19. J Sport Health Sci, 10, 333 – 40. https://doi.org/10.1016/j.jshs.2020.11.007.

[33] Iyizoba N., 2017, Nigeria: Managing Stress in World’s Most Stressful Country. AllAfrica, 2017. Date of access: 5/8/20222. https://allafrica.com/stories/201709140833.html.

[34] ThisDay, 2021, Nigeria: The Stress of Living in Lagos. AllAfrica, 2021. Date of access: 5/8/2022. https://allafrica.com/stories/202106280283.html.

[35] Onigbogi C.B., and Banerjee S., 2019, Prevalence of Psychosocial Stress and Its Risk Factors among Health-care Workers in Nigeria: A Systematic Review and Meta-Analysis. Niger Med J.60(5), 238–244. https://doi:0.4103/nmj.NMJ_67_19.

[36] Ogbujah C, 2014, African Cultural Values and Inter-communal Relations: The Case with Nigeria. Developing Country Studies 2014: 4 (24): 208-17.

[37] Onuoha F., 2015, Onuoha Frank: Locating African Values in Twenty–First Century Economics. ASFL, 2018. Date of access: 5/8/2022. https://www.africanliberty.org/2015/09/09/onuoha-frank-locating-african-values-in-twenty-first-century-economics/.

[38] Sibani C.M., 2018, Impact of Western Culture on Traditional African Society: Problems and Prospects. International Journal of Religion and Human Relations 2018; 10 (1): 56 – 72.

[39] Watson K.,2019, Everything You Need to Know About Premature Ageing. Date of access: 24/11/2020. https://www.healthline.com/health/beauty-skin-care/premature-aging#tips-for-prevention.

[40] Sandoiu A., 2017, Sedentary lifestyle speeds up biological aging, study finds. Date of access: 21/6/2021. https://www.medicalnewstoday.com/articles/315347#Sedentary-women-biologically-older-by-8-years.

[41] Irwin M.R.,2014, Sleep and inflammation in resilient aging. Interface Focus, 4 (20140009), 1 – 7. http://dx.doi.org/10.1098/rsfs.2014.0009.

[42] He M., Deng X., Zhu Y., Huan L., and Niu W., 2020, The relationship between sleep duration and all-cause mortality in the older people: an updated and dose-response meta-analysis. BMC Public Health, 20 (1179), 1 – 18. https://doi.org/10.1186/s12889-020-09275-3.

[43] Korab A., 2021, Everyday Habits That Age You Faster, According to Science: Look younger and be healthier with this essential advice. Date of access: 21/2/2021. https://www.eatthis.com/news-health-habits-age-science/.

[44] Franklin B.A, and Cushman M., 2011, Recent Advances in Preventive Cardiology and Lifestyle Medicine. Circulation, 123, 2274 – 2283.

[45] Miller J., 2011, The Fountain of Youth: The Quest for Biological Immortality. Date of access: 8/5/2021. http://www.slideshare.net/Justin2226/human-longevity-by-justin-miller.

[46] Whitbourne S.K., 2012, What’s Your True Age? You may be a lot younger than you think. Date of access: 8/4/2021. https://www.commonlit.org/texts/what-s-your-true-age.