Effect of a weekly SMS reminder on Adherence and Quality of Life among HIV/AIDS patients on ART in Rural Botswana, Prospective Cohort Study

Download Article

DOI: 10.21522/TIJPH.2013.08.03.Art017

Authors : Lamboly Kumboneki, Lamboly Kumboneki

Abstract:

Objective: Though the use of mobile in the African continent is continuously growing, there are limited evidence on its use and effect on patients on ART. This study assessed the impact of mobile phone technology on adherence and quality of life among HIV/AIDS patients on ART.

Methodology and Design: Between October 2016 and July 2017, we conducted a randomized controlled intervention at Lethlakane Primary Hospital in rural Botswana with 298 patients equally distributed in the intervention and control arm.

Over a period of 24 weeks, we sent weekly SMS to PLHIV on ART and responses were expected within 48h. Messages and scheduled measurements were provided in English and Setswana, according to the participant’s preference.

Results: In intention-to-treat analysis, participants of the intervention arm received weekly SMS and maintained at least 90% of adherence to ART and similar achievement was also recorded in the control arm; However, SMS intervention was significantly associated to improvements in quality of life in the intervention arm (95% of patients) compared to the control arm with only 25% improving their QoL. (p 0.003).

Conclusion: Mobile technology offers a great opportunity to improve accessibility to services and a platform for interaction with patients. Further researches should be conducted to understand how best mobile technology could be used in a cost-effective manner and for better efficiency.

Keywords: Quality of life (QOL), Mobile Technology, Adherence to ART, People living with HIV.

References:

Sidibé M. UNAIDS Data 2017. 2017; 1–248.

[2]. Dennison CR. The role of patient-reported outcomes in evaluating the quality of oncology care. Am J Manag Care. 2002; 8(18 SUPPL.): 580–6.

[3]. Bitswana ARV program.

[4]. Nglazi MD, West SJ, Dave JA, Levitt NS, Lambert E V. Quality of life in individuals living with HIV/AIDS attending a public sector antiretroviral service in Cape Town, South Africa. BMC Public Health. 2014; 14.

[5]. Unaids. Terminology Guidelines. 2011; (OctObER):1–31.

[6]. Arjun BY, Unnikrishnan B, Ramapuram JT, Thapar R, Mithra P, Kumar N, et al. Factors Influencing Quality of Life among People Living with HIV in Coastal South India. J Int Assoc Provid AIDS Care [Internet]. 2017; 16(3):247–53. Available from: https://journals.sagepub.com/doi/10.1177/2325957415599213.

[7]. Outcomes WB, June F. Effects of a Phone Call Intervention to Promote Adherence to Antiretroviral Therapy and Quality of Life of HIV / AIDS Patients in Baoshan, China: A Randomized Controlled Trial Internet-Facilitated, Voluntary Counseling and Testing (VCT) Clinic-Based. 2007; 2013:1–18.

[8]. Tomita A, Garrett N, Werner L, Burns JK, Ngcobo N, Zuma N, et al. Impact of Antiretroviral Therapy on Health-Related Quality of Life among South African Women in the CAPRISA 002 Acute Infection Study. AIDS Behav [Internet]. 2013; 18(9):1801–7. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127113/pdf/nihms599872.pdf

[9]. Liping M, Peng X, Haijiang L, Lahong J, Fan L. Quality of Life of People Living with HIV/AIDS: A Cross-Sectional Study in Zhejiang Province, China. PLoS One [Internet]. 2015; 10(8): e0135705. Available from:

https://dx.plos.org/10.1371/journal.pone.0135705.

[10]. Akinboro AO, Akinyemi SO, Olaitan PB, Raji AA, Popoola AA, Awoyemi OR, et al. Quality of life of Nigerians living with human immunodeficiency virus. Pan Afr Med J [Internet]. 2014; 18:1–11. Available from: https://www.panafrican-med-journal.com/content/article/18/234/full/

[11]. Bakiono F, Guiguimdé PWL, Sanou M, Ouédraogo L, Robert A. Quality of life in persons living with HIV in Burkina Faso: A follow-up over 12 months. BMC Public Health. 2015; 15(1): 1–10.

[12]. Statistics Botswana. Selected statistical indicators 1966-2016: enabling stakeholders formulate policies, plan and make decisions. 2016. 82 p.

[13]. Zahran HS, Kobau R, Moriarty DG, Zack MM, Holt J, Donehoo R. Health-related quality of life surveillance--United States, 1993-2002. MMWR Surveill Summ [Internet]. 2005; 54(4):1–35. Available from: http://www.ncbi.nlm.nih.gov/pubmed/16251867

[14]. Pop-Eleches C, Thirumurthy H, Habyarimana JP, Zivin JG, Goldstein MP, de Walque D, et al. Mobile phone technologies improve adherence to antiretroviral treatment in a resource-limited setting: a randomized controlled trial of text message reminders. Aids. 2013; 25(6):825–34.

[15]. Mbuagbaw L, Thabane L, Ongolo-Zogo P, Lester RT, Mills E, Volmink J, et al. The Cameroon mobile phone SMS (CAMPS) trial: a protocol for a randomized controlled trial of mobile phone text messaging versus usual care for improving adherence to highly active anti-retroviral therapy. Trials. 2011; 12(1):5.