The Importance of Geospatial Data on Multidrug-Resistant and Extensively Drug-resistant Tuberculosis Distribution in Engela District (Namibia): Retrospective cohort study
Abstract:
Background: Multidrug-resistant tuberculosis (MDR-TB) has become a major public
health problem and obstacle to global TB control. MDR-TB is associated with
higher case fatality rates, especially among HIV-infected patients, and is much
more difficult and costlier to treat than drug susceptible TB. Namibia is the
country with the fourth highest TB burden in the world. The incidence rate in
2015 was 651/100 000. Multidrug-resistant tuberculosis (MDR-TB) has become a
major public health problem, especially in developing countries, where the
MDR-TB burden is the highest. In Namibia, among the regions highly affected by
MDR-TB, Ohangwena region is facing many challenges. A recent study has
demonstrated that the magnitude of the problem by numbers, about 40 per cent of
patients admitted to the Katutura State Hospital’s TB unit and 30 per cent of
patients who commenced treatment at the Engela District Hospital in the
Ohangwena Region are Angolan nationals.
Objectives: To determine geospatial Multidrug-resistant and extensively drug-resistant
Tuberculosis Distribution in Angola and Namibia; To investigate the impact of
geospatial distribution on Multidrug-resistant and extensively drug-resistant
Tuberculosis. Methods: this is a retrospective cohort study that will be
performed on all cases of Multidrug-resistant and extensively drug-resistant
Tuberculosis with confirmed laboratory test in Engela District Hospital between
January 2013 and December 2017. Geospatial data will be used to illustrate all
hypotheses.
Conclusion: this study could be crucial on its genre to establish different gaps
between Angolan and Namibian in the management of MDR-TB in Engela district
hospital.
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