Abstract:

Medicinal and natural herbal plant products are traditionally used from long time in many countries. The current work was to evaluate the flavonoid rich fraction in Caralluma attenuate and other phytochemical analysis of stem of the plant. Preliminary phytochemical analysis revealed the presence of phytochemicals such as alkaloids, polyphenols, flavonoids and tannin content in methanol extracts of stem then they were determined spectrometrically. The present study provided, a detailed report on the isolation and characterization of Thin Layer Chromatography from stem of Caralluma attenuate. The methanol extract were used for various biological properties and in vivo assays which is used discovering new drugs.

Keywords: Caralluma attenuata, phytochemical screening, medicinal uses and TLC.

References:

[1]. Ajit K.D, Dutta B. K and Sharma G. D (2007) “Medicinal plants used by different tribes of Cachar district, Assam”. Indian Journal Of traditional KnowledgeVol7 (3), pp 446-454.

[2]. Balasubramanian.P, Rajasekaran.A and Prasad.S.N (1997) “Folk Medicine of the Irulas of Coimbatore Forests”. Ancient Science of Life Vol XVI 3, pages 222 – 226.

[3]. Beckman CH. Phenolic-storing cells: keys to programmed cell death and periderm formation in wilt disease resistance and in general defence responses in plants? Physiol. Mol. Plant Pathol 2000; 57:101-10.

[4]. Brahmachari G. Mother Nature: An inexhaustible source of drugs and lead molecules. In: Brahmachari G, Editor. Chemistry, Biochemistry and Pharmacology. 1 ^st ed. New Delhi: Narosa Publishing House Pvt. Ltd.; 2009. p. 1-20.

[5]. Buenz E.J, Schnepple D.J and Bauer B.A (2004). Techniques: Bioprospecting historical herbal texts by hunting for new leads in old tomes. Trends PharmacolSci 25: pp.494-498.

[6]. Divya. S., Naveen. K.K., Ramachandran. S and Dhanaraju. M. D. (2011) “Wound Healing and In Vitro Antioxidant Activities of Croton bonplandianum Leaf Extract in Rats”. Global Journal of Pharmacology 5 (3): 159-163.

[7]. Kirti S Prabhu, Richard Lobo and Annie Shirwaikar. Antidiabetic properties of the alcoholic extract of Sphaeranthus indicus in streptozotocin-nicotinamide diabetic rats. Journal of Pharmacy and Pharmacology, 2008; 60: 909-16.

[8]. Kovalev S. V. (2009). Flavonoids from Lotus ucrainicus and I. arvensis. Chemistry of Natural Compounds, Vol. 45, No. 4. Pp. 550-551.

[9]. Lenin B.J and Venkat R.S. (2009). “Traditional Uses of Some Medicinal Plants by tribals of Gangaraju Madugula Mandal of Visakhapatnam District, Andhra Pradesh”. Ethnobotanical Leaflets 13: 388-98.

[10]. Mahadeswara Swamy (2006) Ban Tulsi (Online), Available: http://www.flowersofindia.net/catal og/slides/Ban%20Tulsi.html (25 Jul, 2006).

[11]. Scalbert, A., Manach, C., Morand, C., Remesy, C., Jimenez, L., (2005). Dietary polyphenols and the prevention of diseases. Crit. Rev. Food Sci. Nutr. 45, pp.287-306.

[12]. Spencer JP, Abd El Mohsen MM, Minihane AM, Mathers JC. Biomarkers of the intake of dietary polyphenols: strengths, limitations and application in nutrition research. Br J Nutr 2008; 99:12-22.