Abstract:

Critical Appraisal of head-to-head studies is an important decision-making skill. Questions followed by evidence statements are responses that give researchers the evidence-based information they need to make decisions on the best treatment for an indication. The lung is the organ that HIV most frequently infects, and respiratory complications, such as pneumonia, are a common cause of death. The question of interest is: “Which of two treatments is the best one to mitigate lung infections in poor HIV patients?” This paper is a critical appraisal done to find an antibiotic that may be best for poverty-stricken HIV patients with pneumonia. There have been many reports of substandard drugs being donated to poorer countries. Critical appraisals need to be done on certain drugs that are donated to poverty-stricken countries to see if the drug is cost-effective, useful and affordable. It should be unethical to donate useless drugs to vulnerable poor HIV patients with lung infections.

Keywords: Critical appraisal, Decisionmaking, Randomized Controlled Trial (RCT) Human Immunodeficiency Virus (HIV) 

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