Meta-Analysis: A Key Statistical Method in Clinical Research Through A Review of Preterm Birth and Childhood Wheezing Disorders
Abstract:
Meta-analysis is a statistical approach to combine the data
derived from a systematic-review. Therefore, every meta-analysis should be
based on an underlying systematic review, but not every systematic review leads
to a meta-analysis. Meta-analysis offers a rational and helpful way of
dealing with a number of practical difficulties that beset anyone trying to
make sense of effectiveness research.
This article review was written after details and
critical assessment of the research conducted by Been JV et.al. The researchers
undertook meta-analysis and a systematic review investigating risks of
asthma/wheezing disorders in children born preterm, including the increasing
numbers who, as a result of advances in neonatal care, now survive very preterm
birth. The trigger of research was accumulating evidence which implicates early
life factors in the aetiology of non-communicable diseases, including
asthma/wheezing disorders.
It was evident that preterm birth particularly very
preterm birth increases the risk of asthma. Been JV et.al concluded that these
is greater need to focus on understanding mechanisms and translate it into
preventive actions.
KEY WORDS
Meta-analysis,
Systemic Review, Preterm Birth, Asthma, Wheezing, Disorders
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