Uptake of Artemisinin-based Combination Therapy for Treatment of Acute Malaria at Federal Capital Territory Abuja, Nigeria: a Retrospective Hospital Based Study

Download Article

DOI: 10.21522/TIJAR.2014.05.02.Art004

Authors : Ibrahim S. A, Ukaga C N

Abstract:

Malaria remains a major public health challenge in Abuja. Considerable efforts have been made to reduce the prevalence of the disease; however, the last decade of malaria control has witnessed increased support by government and its partners in the areas of mass distribution of long-lasting insecticidal nets (LLINs) and a massive scale up in malaria case management. Consequently, it has become necessary to provide evidence-based data on the status of progress towards malaria control. A retrospective hospital based study on the uptake of Artemisinin-based Combination Therapy drug for treatment of acute malaria was carried out using a five years hospital records from Wuse District Hospital Abuja. All the records of patients diagnosed with malaria confirmed by Giemsa stained thick and thin peripheral blood films were considered. Data was entered and analyzed using SPSS Chicago version 25. Appropriate tables and mean numbers were displayed. A chi square test was performed to determine the level of significance using 95% confidence interval and p- value. Findings revealed a total of 22,934 patients were diagnosed with acute malaria based on hospital records. Only 48.4% of the patients received Artemisinin Combination Therapy (ACT) drugs. 32.1% of the patients were given non-ACT drugs, 9.3% of patients received Sulfadoxine – Pyrimethamine, 7.59% were given Chloroquine. The study concluded that, The use of Artemisin base Combination Therapy (ACT) as recommended by WHO has a significant influence on malaria treatment outcome.

Keywords: Artemisinin-based Combination Therapy, Malaria, Uptake, Malaria.

References:

[1].     Alexander Dodoo et al (2009) Pattern of drug utilization for treatment of uncomplicated malaria in urban Ghana following national treatment policy change to artemisinin-combination therapy. Malar J. 2009;8 2 Published online 2009 Jan 5. doi: 10.1186/1475-2875-8-2.

[2].     Charles C Ezenduka et al (2014). Drugs use pattern for uncomplicated malaria in medicine retail outlets in Enugu urban, southeast Nigeria: implications for malaria treatment policy Malar J. 2014;13: 243. Published online 2014 Jun 24. doi: 10.1186/1475-2875-13-243.

[3].     Chedi, b. a. z, et al (2010) Interventional studies of anti-malarial drugs utilization in public health facilities in kano, Nigeria.

[4].     Etuk E U, Egua M A, Muhammad A A (2008). Prescription pattern of antimalarial drugs in children below 5 years in a tertiary health institution in Nigeria. Ann Afr Med [serial online] 2008 [cited 2018 Jun 1]; 7:24-8. Available from: http://www.annalsafrmed.org/text.asp?2008/7/1/24/55688.

[5].     Federal Capital Territory Health Statistics Bulletin 2016.

[6].     Federal Ministry of Health and National Malaria Elimination Programme [NMEP] 2014).

[7].     National Bureau of Statistics (NBS), National Malaria Indicator Survey (NMIS), 2015.

[8].     Samuel Chatio, et al (2015) Adherence and Uptake of Artemisinin-Based Combination Treatments for Uncomplicated Malaria: A Qualitative Study in Northern Ghana. PLoS One. 2015; 10(2): e0116856.Published online 201. doi: 10.1371/journal.pone.0116856.

[9].   Timothy Davis et al (2005). Artemisinin-based combination therapies for uncomplicated malariaMed J Aust 2005; 182 (4): 181-185. Published online.

[10]. World Health Organization (WHO) Global malaria report 2000.

[11]. World Health Organization (WHO) Global malaria report 2014.

[12]. WHO manual on drug utilization 2003.